KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S1PR1
All Species:
16.97
Human Site:
Y22
Identified Species:
37.33
UniProt:
P21453
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21453
NP_001391.2
382
42811
Y22
S
V
S
D
Y
V
N
Y
D
I
I
V
R
H
Y
Chimpanzee
Pan troglodytes
XP_513598
382
42768
Y22
S
V
S
D
Y
V
N
Y
D
I
I
V
R
H
Y
Rhesus Macaque
Macaca mulatta
XP_001107778
331
36908
Dog
Lupus familis
XP_547259
382
42503
Y22
P
V
S
D
Y
V
N
Y
D
I
I
V
R
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
O08530
382
42595
Y22
S
V
S
D
Y
G
N
Y
D
I
I
V
R
H
Y
Rat
Rattus norvegicus
P48303
383
42727
Y23
Q
V
S
D
Y
G
N
Y
D
I
I
V
R
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520197
378
41947
I22
P
D
Y
V
N
Y
D
I
I
I
R
H
Y
N
Y
Chicken
Gallus gallus
XP_422305
379
42371
V23
T
N
T
D
V
N
Y
V
I
K
E
H
Y
N
Y
Frog
Xenopus laevis
Q9PU17
366
41345
A20
S
M
M
S
Q
T
S
A
A
S
E
S
Q
C
Y
Zebra Danio
Brachydanio rerio
Q9DDK4
362
40583
R16
Y
N
F
T
G
K
F
R
K
V
H
K
D
P
G
Tiger Blowfish
Takifugu rubipres
Q9PUQ8
384
42694
V23
K
L
D
H
R
P
T
V
G
T
S
P
G
T
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85
95
N.A.
93.9
93.2
N.A.
85.8
84.2
36.6
68
48.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
85.5
97.6
N.A.
96.8
96.3
N.A.
89.5
90.3
59.6
80.3
69.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
93.3
86.6
N.A.
13.3
13.3
13.3
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
93.3
N.A.
93.3
86.6
N.A.
26.6
33.3
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
10
55
0
0
10
0
46
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
19
0
0
10
0
0
0
10
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
19
0
46
0
% H
% Ile:
0
0
0
0
0
0
0
10
19
55
46
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
10
10
46
0
0
0
0
0
0
19
0
% N
% Pro:
19
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
10
0
46
0
10
% R
% Ser:
37
0
46
10
0
0
10
0
0
10
10
10
0
0
0
% S
% Thr:
10
0
10
10
0
10
10
0
0
10
0
0
0
10
0
% T
% Val:
0
46
0
10
10
28
0
19
0
10
0
46
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
46
10
10
46
0
0
0
0
19
0
73
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _